Protecting kidneys from damage: The crucial role of PCK1

A new study from the Nephrology Lab, published in Kidney International, shows that the enzyme PCK1 plays a crucial role in protecting kidney cells after injury. When PCK1 is missing, kidney cells can’t produce enough energy, leading to inflammation and scarring. These findings suggest that boosting PCK1 activity could help slow down or prevent the progression of chronic kidney disease. https://www.kidney-international.org/article/S0085-2538(25)00513-7/fulltext